35.1 Infectious Disease

THINK ABOUT IT about it For thousands of years, people believed that diseases were caused by curses, evil spirits, or vapors rising from foul marshes or dead plants and animals. In fact, malaria was named after the Italian words mal aria, meaning “bad air.” This isn't all that surprising, because, until microscopes were invented, most causes of disease were invisible to the human eye!

Causes of Infectious Disease

What causes infectious disease?

During the mid-nineteenth century, French chemist Louis Pasteur and German bacteriologist Robert Koch established a scientific explanation for infectious disease. Pasteur's and Koch's observations and experiments led them to conclude that infectious diseases occur when microorganisms cause physiological changes that disrupt normal body functions. Microorganisms were commonly called “germs,” so this conclusion was called the germ theory of disease. That's unfortunate now, because the word germ has no scientific meaning.

Agents of Disease If germ isn't a scientific term, how should we describe the causes of infectious disease? Infectious diseases can be caused by viruses, bacteria, fungi, “protists”, and parasites. Except for parasites, most of these disease-causing microorganisms are called pathogens. Figure 35–1 provides more information and examples of pathogens and parasites.

An illustration showing five agents of diseases.

FIGURE 35–1 Examples of Agents of Disease Infectious diseases are caused by pathogens and parasites—organisms that invade a body and disrupt its normal functions.

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Table of Contents

Miller & Levine Biology UNIT 1 The Nature of Life UNIT 2 Ecology UNIT 3 Cells UNIT 4 Genetics UNIT 5 Evolution UNIT 6 From Microorganisms to Plants UNIT 7 Animals UNIT 8 The Human Body A Visual Guide to The Diversity of Life Appendices Glossary Index Credits