Autoimmune Diseases Sometimes a disease occurs in which the immune system fails to properly recognize “self,” and attacks cells or compounds in the body as though they were pathogens. When the immune system attacks the body's own cells, it produces an autoimmune disease. Examples of autoimmune diseases are Type I diabetes, rheumatoid arthritis, and lupus.

In Type I diabetes, antibodies attack insulin-producing cells in the pancreas. In rheumatoid arthritis, antibodies attack tissues around joints. Lupus is an autoimmune disease in which antibodies attack organs and tissues causing areas of chronic inflammation throughout the body.

Some autoimmune diseases can be treated with medications that alleviate specific symptoms. For example, people with Type I diabetes can take insulin. Other autoimmune diseases are treated with medications that suppress the immune response. However, these medications also decrease the normal immune response and must be monitored.

HIV and AIDS

What causes AIDS and how is it spread?

During the late 1970s, physicians began reporting serious infections produced by microorganisms that didn't normally cause disease. Previously healthy people began to suffer from Pneumocystis carinii pneumonia, Kaposi sarcoma (a rare form of skin cancer), and fungal infections of the mouth and throat. Because these diseases are normally prevented by a healthy immune response, doctors concluded that these patients must have weakened immune systems. Diseases that attack a person with a weakened immune system are called opportunistic diseases. Researchers concluded that these illnesses were symptoms of a new disorder they called acquired immunodeficiency syndrome (AIDS). Research eventually revealed that this “syndrome” was an infectious disease caused by a pathogen new to science.


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Table of Contents

Miller & Levine Biology UNIT 1 The Nature of Life UNIT 2 Ecology UNIT 3 Cells UNIT 4 Genetics UNIT 5 Evolution UNIT 6 From Microorganisms to Plants UNIT 7 Animals UNIT 8 The Human Body A Visual Guide to The Diversity of Life Appendices Glossary Index Credits