An illustration showing the tightly coiled chromosome of an eukaryotic cell during cell division. The structures labeled are:
 Duplicated chromosome,
 Sister chromatids,
 Nucleosome,
 Supercoils,
 Centromere,
 DNA double helix,
 Histone proteins, and
 Coils.

FIGURE 10–5 Eukaryotic Chromosome As a eukaryotic cell prepares for division, each chromosome coils more and more tightly to form a compact structure. Interpret Visuals Which side of the diagram, left or right, shows the smallest structures, and which shows the largest?

Eukaryotic Chromosomes Eukaryotic cells generally have much more DNA than prokaryotes have and, therefore, contain multiple chromosomes. Fruit flies, for example, have 8 chromosomes per cell, human cells have 46, and carrot cells have 18. The chromosomes in eukaryotic cells form a close association with histones, a type of protein. This complex of chromosome and protein is referred to as chromatin. DNA tightly coils around the histones, and together, the DNA and histone molecules form beadlike structures called nucleosomes. Nucleosomes pack together to form thick fibers, which condense even further during cell division. Usually the chromosome shape you see drawn is a duplicated chromosome with supercoiled chromatin, as shown in Figure 10–5.

Why do cells go to such lengths to package their DNA into chromosomes? One of the principal reasons is to ensure equal division of DNA when a cell divides. Chromosomes make it possible to separate DNA precisely during cell division.

In Your Notebook Write instructions to build a eukaryotic chromosome.

The Cell Cycle

What are the main events of the cell cycle?

Cells go through a series of events known as the cell cycle as they grow and divide. During the cell cycle, a cell grows, prepares for division, and divides to form two daughter cells. Each daughter cell then moves into a new cell cycle of activity, growth, and division.


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Table of Contents

Miller & Levine Biology UNIT 1 The Nature of Life UNIT 2 Ecology UNIT 3 Cells UNIT 4 Genetics UNIT 5 Evolution UNIT 6 From Microorganisms to Plants UNIT 7 Animals UNIT 8 The Human Body A Visual Guide to The Diversity of Life Appendices Glossary Index Credits