Duplicate Genes Evolve What's so important about gene duplication? Think about using a computer to write an essay for English class. You then want to submit a new version of the essay to your school newspaper. So, you make an extra copy of the original file and edit it for the newspaper.

Duplicate genes can work in similar ways. Sometimes, extra copies of a gene undergo mutations that change their function. The original gene is still around, just like the original copy of your English essay. So, the new genes can evolve without affecting the original gene function or product. Figure 17–19 shows how this happens.

Gene Families Multiple copies of a duplicated gene can turn into a group of related genes called a gene family. Members of a gene family typically produce similar, yet slightly different, proteins. Your body, for example, produces a number of molecules that carry oxygen. Several of these compounds—called globins—are hemoglobins. The globin gene family that produces them evolved, after gene duplication, from a single ancestral globin gene. Some of the most important evolution research focuses on another gene family—Hox genes.

A flowchart of 'Gene Duplication.'

FIGURE 17–19 Gene Duplication In this diagram, a gene is first duplicated, and then one of the two resulting genes undergoes mutation.

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Developmental Genes and Body Plans

How may Hox genes be involved in evolutionary change?

One exciting new research area is nicknamed “evo-devo” because it studies the relationship between evolution and embryological development. Darwin himself had a hunch that changes in the growth of embryos could transform adult body shape and size. Researchers now study how small changes in Hox gene activity could produce the kinds of evolutionary changes we see in the fossil record.


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Table of Contents

Miller & Levine Biology UNIT 1 The Nature of Life UNIT 2 Ecology UNIT 3 Cells UNIT 4 Genetics UNIT 5 Evolution UNIT 6 From Microorganisms to Plants UNIT 7 Animals UNIT 8 The Human Body A Visual Guide to The Diversity of Life Appendices Glossary Index Credits