Nonsteroid Hormones Nonsteroid hormones generally cannot pass through the cell membrane of their target cells. Nonsteroid hormones bind to receptors on cell membranes and cause the release of secondary messengers that affect cell activities. Figure 34–3 shows the action of nonsteroid hormones in cells.

  1. A nonsteroid hormone binds to receptors on the cell membrane.

  2. The binding of the hormone activates enzymes on the inner surface of the cell membrane.

  3. These enzymes release secondary messengers such as calcium ions, nucleotides, and even fatty acids to relay the hormone's message within the cell. One common secondary messenger is cAMP (cyclic AMP), which is produced from ATP.

  4. These secondary messengers can activate or inhibit a wide range of cell activities.

Steroid and nonsteroid hormones can have powerful effects on their target cells. It is therefore especially important to understand the ways in which the endocrine system regulates their production and release into the blood.

A diagram showing the action of nonsteroid hormones in the cell.

FIGURE 34–3 Nonsteroid Hormones Nonsteroid hormones bind to receptors on a target cell membrane and cause the release of secondary messengers that affect cell activities.

d


End ofPage 981

Table of Contents

Miller & Levine Biology UNIT 1 The Nature of Life UNIT 2 Ecology UNIT 3 Cells UNIT 4 Genetics UNIT 5 Evolution UNIT 6 From Microorganisms to Plants UNIT 7 Animals UNIT 8 The Human Body A Visual Guide to The Diversity of Life Appendices Glossary Index Credits